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Intravenous Gammaglobulin (IVIG)

IVIG is derived from human plasma and contains a wide range of antibodies normally found in healthy individuals. It is thought to work by blocking the mechanism that causes platelets to be destroyed in the spleen.

IVIG is given intravenously (through the vein). Each treatment may require several hours and be repeated every 1-5 days. Treatment may raise platelet levels for three to four weeks. Some patients may experience such side effects as:

  • Headaches
  • Fever
  • Chills

Other possible side effects may include kidney problems, lung problems, heart attacks, or strokes.1,2  Please report any side effects to your physician as soon as possible.Because IVIG is made from human plasma, special processes are used in preparation of IGIV to safeguard against known viruses that may be found in human blood. However, the potential to transmit infectious agents cannot be totally eliminated.

Always seek the advice of your own physician or other qualified healthcare professional regarding any medical conditions.

  1. Sandler S.G. and Tutuncuoglu S.O. Immune Thrombocytopenic Purpura -- current management practices. Expert Opin Pharmacother. 2004; 5(12): 2515-2527.
  2. Grabenstein J.D. ImmunoFacts: Vaccines and Immunologic Drugs. St. Louis, MO: Wolters Kluwer Health Inc; 2006.