WinRho® SDF
Baxter is proud to be the US distributor for WinRho® SDF [Rho(D) Immune Globulin Intravenous (Human)] – the first Anti-D immunoglobulin treatment approved for ITP.
How WinRho® SDF Works
WinRho® SDF is a concentration of antibodies that specifically bind to Rh-positive red blood cells. “Rh” refers to a particular protein on the outside of the red blood cell. If your red blood cells have this protein, your blood type is “Rh-positive”; if they don’t, your blood type is “Rh-negative”. About 85% of the population is Rh-positive.
When administered to an Rh-positive patient, WinRho® SDF is thought to coat the Rh-positive red cells, causing their destruction by the spleen, thereby preventing the destruction of platelets. This results in increased levels of circulating platelets and an alleviation of the symptoms of ITP.
For a visual demonstration of the presumed mechanism of action for WinRho® SDF, please click on the icon.Indications and Usage
WinRho® SDF must be administered via the intravenous route when used in
clinical situations requiring an increase in platelet count to prevent excessive hemorrhage in the treatment of non-splenectomized, Rho(D) positive:
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The safety and efficacy of WinRho® have not been evaluated in clinical
trials for patients with non-ITP causes of thrombocytopenia or in previously
splenectomized patients or in patients who are Rho(D) negative.
Please see Important Safety Information and Prescribing Information.
